Commensal bacterial-derived retinoic acid primes host defense to intestinal infection
T. Alenghat, V. Woo, E. M. Eshleman, J. Whitt, S. Hashimoto-Hill, S.-e. Wu, L. Engleman, T. Rice, R. Karns, B. A. Vallance
This study identifies retinoic acid (RA) as a microbiota-derived metabolite that enhances intestinal defense against infection by modulating host gene expression.
bioRxiv · Jan 27, 2021Microbiology