Cortical anchoring of the microtubule cytoskeleton is essential for neuron polarity and functioning
L. He, R. Koostra, R. Das, E. Oudejans, E. V. van Leen, J. Ziegler, S. Portegies, B. de Haan, A. S. van Regteren Altena, R. Stucchi, A. F. M. Altelaar, S. Wieser, M. Krieg, C. C. Hoogenraad, M. Harterink
The paper identifies UNC-119 as a key protein linking Ankyrin and CRMP to anchor microtubules in neurons, essential for maintaining polarity and function.
bioRxiv · Sep 26, 2019Cell Biology