Author

R. Kueppers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. Seifert· 3 shared A. Kibler· 2 shared B. Budeus· 2 shared C. C. Oakes· 2 shared E. Homp· 2 shared J. Duerig· 2 shared K. Bronischewski· 2 shared M. Brauser· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

M. Seifert

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A heterogeneous pool of tumor precursor cells with self-replenishing and tumor-originating properties in Chronic Lymphocytic Leukemia

B. Budeus, M. Dampmann, A. Kibler, B. Fassbender, M. Brauser, K. Bronischewski, E. Homp, S. Taudien, P. Johansson, J. Bloehdorn, S. Stilgenbauer, J. von Tresckow, J. Duerig, H. C. Reinhardt, R. Kueppers, , M. Seifert

The paper identifies a heterogeneous subpopulation of CLL-related B cells with self-replenishing and tumor-initiating properties that contribute to disease progression and clonal evolution.

bioRxiv · May 4, 2022 · PreprintCancer Biology

Human neonatal B cell immunity differs from the adult version by conserved Ig repertoires and rapid, but transient response dynamics

B. Budeus, A. Kibler, M. Brauser, E. Homp, K. Bronischewski, A. Ross, A. Goergens, M. A. Weniger, J. Dunst, T. Kreslavskiy, S. Vitoriano, F. Murke, C. C. Oakes, P. Rusch, D. Andrikos, , M. Seifert

This study shows that human cord blood B cells are mature and functional but have distinct transcriptional programs and rapid, transient response dynamics compared to adult B cells.

bioRxiv · Aug 11, 2020 · PreprintImmunology

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

J. A. Wierzbinska, R. Toth, N. Ishaque, K. Rippe, J.-P. Mallm, L. Klett, D. Mertens, T. Zenz, T. Hielscher, M. Seifert, R. Kueppers, Y. Assenov, P. Lutsik, S. Stilgenbauer, P. M. Roessner, , D. B. Lipka

This study introduces Methyl-COOM, a method to identify cell-of-origin and CLL-specific epigenetic aberrations by analyzing DNA methylation patterns.

bioRxiv · Feb 4, 2020Cancer Biology