Alternative Splicing of MR1 regulates antigen presentation to MAIT cells
G. A. Narayanan, A. Nellore, J. Tran, A. H. Worley, E. W. Meermeier, E. Karamooz, M. Huber, R. Kurapova, F. Tafesse, M. J. Harriff, D. M. Lewinsohn
This study investigates how alternative splicing of MR1 affects antigen presentation to MAIT cells, finding that only MR1A can activate MAIT cells while MR1B inhibits their activation.
bioRxiv · Jul 11, 2019Immunology