Author

R. L. D. Labitigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

J. A. Theriot· 2 shared A. L. Sanborn· 1 shared A. P. van Loon· 1 shared C. K. Chan· 1 shared C. V. Hao· 1 shared D. Vorselen· 1 shared E. M. Brown· 1 shared E. Peterman· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

J. A. Theriot

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Author profile →

2 papers

Recent·Most cited

Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening

R. L. D. Labitigan, A. L. Sanborn, C. V. Hao, C. K. Chan, N. M. Belliveau, E. M. Brown, M. Mehrotra, J. A. Theriot

This study uses CRISPRi screening and deep learning to identify genes affecting cell morphology and construct a quantitative morphological variation space in human cells.

bioRxiv · Dec 27, 2022 · PreprintCell Biology

Cell surface receptors TREM2, CD14 and integrin αMβ2 drive sinking engulfment in phosphatidylserine-mediated phagocytosis

D. Vorselen, R. A. Kamber, R. L. D. Labitigan, A. P. van Loon, E. Peterman, M. K. Delgado, S. Lin, J. P. Rasmussen, M. C. Bassik, J. A. Theriot

This study identifies TREM2, CD14, and integrin αMβ2 as essential cell surface receptors for PS-mediated phagocytosis, revealing distinct mechanisms for PS and antibody-coated target uptake.

bioRxiv · Jul 30, 2022 · PreprintCell Biology