Author

N. M. Belliveau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5 Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 4 Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 4 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:differential expression· 3 Organism:E. coli· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2

Frequent Co-Authors

R. Phillips· 6 shared S. L. Barnes· 4 shared G. Chure· 3 shared J. B. Kinney· 3 shared W. T. Ireland· 3 shared A. Moradian· 2 shared J. A. Theriot· 2 shared M. J. Sweredoski· 2 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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6 shared papersBiophysics

R. Phillips

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Author profile →

8 papers

Recent·Most cited

Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening

R. L. D. Labitigan, A. L. Sanborn, C. V. Hao, C. K. Chan, N. M. Belliveau, E. M. Brown, M. Mehrotra, J. A. Theriot

This study uses CRISPRi screening and deep learning to identify genes affecting cell morphology and construct a quantitative morphological variation space in human cells.

bioRxiv · Dec 27, 2022 · PreprintCell Biology

Cell migration CRISPRi screens in human neutrophils reveal regulators of context-dependent migration and differentiation state

N. M. Belliveau, M. J. Footer, E. Akdogan, A. P. van Loon, S. R. Collins, J. A. Theriot

The paper uses CRISPRi screens in human neutrophils to identify genes regulating context-dependent migration and differentiation.

bioRxiv · Dec 16, 2022 · PreprintCell Biology

Deciphering the regulatory genome of Escherichiacoli, one hundred promoters at a time

W. T. Ireland, S. M. Beeler, E. Flores-Bautista, N. M. Belliveau, M. J. Sweredoski, A. Moradian, J. B. Kinney, R. Phillips

The paper introduces a method to characterize promoter regulation in E. coli by analyzing 100 promoters across 12 growth conditions, identifying regulatory elements and transcription factors.

bioRxiv · Jan 18, 2020Biophysics

Sequence-Dependent Dynamics of Synthetic and Endogenous RSSs in V(D)J Recombination

S. Hirokawa, G. Chure, N. M. Belliveau, G. A. Lovely, M. Anaya, D. G. Schatz, D. Baltimore, R. Phillips

The paper quantifies sequence-dependent dynamics of RAG-RSS interactions in V(D)J recombination, revealing how single-bp changes affect PC formation, stability, and cleavage.

bioRxiv · Oct 4, 2019Immunology

The Energetics of Molecular Adaptation in Transcriptional Regulation

G. Chure, M. Razo-Mejia, N. M. Belliveau, T. Einav, Z. A. Kaczmarek, S. L. Barnes, M. Lewis, R. Phillips

The paper links mutations in a transcriptional repressor to biophysical parameters, showing how changes in free energy predict gene expression and epistasis.

bioRxiv · May 15, 2019Biophysics

Mapping DNA sequence to transcription factor binding energy in vivo

S. L. Barnes, N. M. Belliveau, W. T. Ireland, J. B. Kinney, R. Phillips

This study develops a method to map DNA sequences to transcription factor binding energy using in vivo data, achieving predictions within 1 kBT of measured values and exploring sequence-context relationships.

bioRxiv · May 25, 2018Biophysics

A systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria

N. M. Belliveau, S. L. Barnes, W. T. Ireland, D. L. Jones, M. J. Sweredoski, A. Moradian, S. Hess, J. B. Kinney, R. Phillips

The paper introduces a systematic method combining assays and modeling to dissect bacterial promoter mechanisms at nucleotide resolution.

bioRxiv · Jan 6, 2018Biophysics

Tuning transcriptional regulation through signaling: A predictive theory of allosteric induction

M. Razo-Mejia, S. L. Barnes, N. M. Belliveau, G. Chure, T. Einav, M. Lewis, R. Phillips

The paper develops a predictive theory of allosteric transcriptional regulation using the Monod-Wyman-Changeux model and validates it with experimental data on bacterial simple repression motifs.

bioRxiv · Jun 26, 2017Biophysics