Author

R. L. Heise

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

K. Shankar· 2 shared M. S. Valentine· 2 shared A. M. Reynolds· 1 shared B. M. Young· 1 shared C. K. Tho· 1 shared D. E. Conway· 1 shared E. N. Wandling· 1 shared F. J. K. Gninzeko· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBioengineering

K. Shankar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mechanical Ventilation induced P21 in an Acute Aging Model of Lung Injury

F. J. K. Gninzeko, C. K. Tho, M. S. Valentine, E. N. Wandling, R. L. Heise

This study investigates how mechanical ventilation contributes to senescence-like changes in lung injury, finding increased P21 and DNA damage markers.

bioRxiv · Mar 8, 2022 · PreprintCell Biology

A Two-Step Bioreactor for Lung Recellularization

B. M. Young, L.-A. M. Antczak, K. Shankar, R. L. Heise

This paper introduces a two-step bioreactor for lung recellularization that improves cell distribution and growth compared to traditional methods.

bioRxiv · Nov 2, 2020 · PreprintBioengineering

Mechanochemical coupling and junctional forces during collective cell migration

J. Bui, D. E. Conway, R. L. Heise, S. H. Weinberg

This study models mechanochemical interactions and junctional forces in collective cell migration, showing biphasic feedback between mechanical tension and Rho GTPase activity, and how junctional forces influence migration speed and tissue size.

bioRxiv · Feb 22, 2019Biophysics

The Influence of Aging and Mechanical Stretch in Alveolar Epithelium ER Stress and Inflammation

M. S. Valentine, J. A. Herbert, P. A. Link, F. J. Kamga Gninzeko, M. B. Schneck, K. Shankar, J. Nkwocha, A. M. Reynolds, R. L. Heise

This study investigates how aging and mechanical stretch increase ER stress and inflammation in alveolar epithelial cells, showing that 4-PBA reduces these effects.

bioRxiv · Jun 30, 2017Bioengineering