Author

R. Lal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:virus· 3 Assay:whole-genome sequencing· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:phylogenetics / evolution· 2 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

R. Kumar· 3 shared S. Nagar· 3 shared U. Sood· 3 shared C. Talwar· 2 shared H. Verma· 2 shared K. Ponnusamy· 2 shared M. Singh· 2 shared M. Verma· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersMicrobiology

R. Kumar

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Monkey Pox Virus (MPXV): Phylogenomics, Host-Pathogen Interactome, and Mutational Cascade

R. Kumar, S. Nagar, S. Haider, U. Sood, K. Ponnusamy, G. G. Dhingra, S. Anand, A. Dua, M. Singh, M. Senger, I. K. Singh, R. Lal

This study analyzes Monkeypox virus genome sequences to investigate its phylogenomics, host-pathogen interactions, and mutational patterns, identifying key proteins and mutations associated with evolutionary dynamics and host evasion.

bioRxiv · Jul 25, 2022 · PreprintMicrobiology

Microbial ecology of sulfur biogeochemical cycling at a mesothermic hot spring atop Northern Himalayas, India

S. Nagar, C. Talwar, M. Motelica-Heino, H.-h. Richnow, M. Shakarad, R. Lal, R. Negi

This study investigates sulfur cycling microbes in a Himalayan hot spring using metagenomics, revealing key bacterial groups and gene families involved in sulfur metabolism and their evolutionary relationships.

bioRxiv · Dec 2, 2021 · PreprintMicrobiology

Comparative Genomics and Integrated Network Approach Unveiled Undirected Phylogeny Patterns, Co-mutational Hotspots, Functional Crosstalk and Regulatory Interactions in SARS-CoV-2

V. Gupta, S. Haider, M. Verma, N. Singhvi, K. Ponnusamy, M. Z. Malik, H. Verma, R. Kumar, U. Sood, P. Hira, S. Satija, R. Lal, Y. Singh

The paper analyzes SARS-CoV-2 genomic variations and host-pathogen interactions to identify mutational patterns, co-mutations, and functional implications in USA strains.

bioRxiv · Jun 20, 2020 · PreprintMicrobiology

Chemoinformatic-guided engineering of polyketide synthases

A. Zargar, R. Lal, L. Valencia, J. Wang, T. Backman, P. Cruz-Morales, A. Kothari, M. Werts, A. Wong, C. B. Bailey, A. Loubat, Y. Liu, Y. Chen, V. Benites, S. Chang, , J. D. Keasling

This study uses chemoinformatics to engineer polyketide synthases for producing saturated β-carbon compounds, finding a correlation between chemical similarity and product titers.

bioRxiv · May 10, 2020Biochemistry

Comparative Genomic Analysis of Rapidly Evolving SARS-CoV-2 Viruses Reveal Mosaic Pattern of Phylogeographical Distribution

R. Kumar, H. Verma, N. Singhvi, U. Sood, V. Gupta, M. Singh, R. Sharma, P. Hira, S. Nagar, C. Talwar, N. Nayyar, S. Anand, C. D. Rawat, M. Verma, R. K. Negi, , R. Lal

This study analyzes SARS-CoV-2 genomes from global isolates to reveal mosaic phylogeographical patterns and identify unique mutations associated with immune evasion mechanisms.

bioRxiv · Mar 25, 2020Microbiology