Author

R. Loos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Kater· 1 shared A. V. Ratushny· 1 shared B. Van Driel· 1 shared C. C. Santini· 1 shared D. De Rooij· 1 shared D. Lashgari· 1 shared D. W. Pierce· 1 shared E. Eldering· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Kater

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

In vitro lymph node-mimicking 3D model displays long-term T cell-dependent CLL proliferation and survival

M. V. Haselager, B. Van Driel, E. Perelear, D. De Rooij, D. Lashgari, R. Loos, A. Kater, P. Moerland, E. Eldering

This paper introduces a 3D in vitro model of the lymph node microenvironment that supports long-term CLL cell proliferation and survival in response to T cell signals and drug treatments.

bioRxiv · Apr 3, 2023Cancer Biology

Quantitative systems pharmacology modeling of avadomide-induced neutropenia enables virtual clinical dose and schedule finding studies

R. A. Abbiati, M. Pourdehnad, S. Carrancio, D. W. Pierce, S. Kasibhatla, M. McConnell, M. W. B. Trotter, R. Loos, C. C. Santini, A. V. Ratushny

The paper uses QSP modeling to simulate avadomide-induced neutropenia and identify optimal dosing schedules for clinical trials.

The AAPS Journal · Aug 27, 2021Peer-reviewedPharmacology & Toxicology