Author

S. Kasibhatla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:clinical cohort / trial· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. B. Pinkerton· 1 shared A. Steffy· 1 shared A. V. Ratushny· 1 shared C. A. Hassig· 1 shared C. C. Santini· 1 shared C. Curtis· 1 shared D. W. Pierce· 1 shared E. J. Curtis· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. B. Pinkerton

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

J. Tang, N. E. Weiser, G. Wang, S. Chowdhry, E. J. Curtis, Y. Zhao, I. T.-L. Wong, G. K. Marinov, R. Li, P. Hanoian, E. Tse, R. Hansen, J. Plum, A. Steffy, S. Milutinovic, , H. Y. Chang

This paper identifies transcription-replication conflict as a vulnerability in ecDNA-containing cancers and demonstrates that CHK1 inhibition selectively kills these tumors.

bioRxiv · Mar 29, 2024 · PreprintCancer Biology

Quantitative systems pharmacology modeling of avadomide-induced neutropenia enables virtual clinical dose and schedule finding studies

R. A. Abbiati, M. Pourdehnad, S. Carrancio, D. W. Pierce, S. Kasibhatla, M. McConnell, M. W. B. Trotter, R. Loos, C. C. Santini, A. V. Ratushny

The paper uses QSP modeling to simulate avadomide-induced neutropenia and identify optimal dosing schedules for clinical trials.

The AAPS Journal · Aug 27, 2021Peer-reviewedPharmacology & Toxicology