Author

I. Meulenbelt

Primary ORCID profile (0000-0001-7786-7081 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

I. MeulenbeltiD1 paper · Leiden University Medical Center

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

R. Coutinho de Almeida· 2 shared A. De Roover· 1 shared A. Rodriguez Ruiz· 1 shared A. Sermon· 1 shared E. H. E. D. Suchiman· 1 shared E. Houtman· 1 shared F. Cornelis· 1 shared G. M. C. Janssen· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

R. Coutinho de Almeida

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2 papers

Recent·Most cited

WWP2 osteoarthritis risk allele rs1052429-A confers risk by affecting cartilage matrix deposition via hypoxia associated genes

M. Tuerlings, G. M. C. Janssen, I. Boone, M. van Hoolwerff, A. Rodriguez Ruiz, E. Houtman, E. H. E. D. Suchiman, R. J. P. van der Wal, R. G. H. H. Nelissen, R. Coutinho de Almeida, P. A. van Veelen, Y. F. M. Ramos, I. Meulenbelt

This study investigates how the OA risk allele rs1052429-A affects cartilage matrix deposition through WWP2 upregulation and hypoxia-related genes in a 3D in vitro model.

bioRxiv · Mar 31, 2022 · PreprintCell Biology

ANP32A represses Wnt signaling across tissues tissues thereby protecting against joint and heart disease

S. Monteagudo, F. Cornelis, X. Wang, A. De Roover, T. Peeters, J. Quintiens, A. Sermon, R. Coutinho de Almeida, I. Meulenbelt, R. Lories

This study identifies ANP32A as a repressor of Wnt signaling that protects against joint and heart disease by inhibiting Wnt target genes and oxidative stress.

bioRxiv · Apr 4, 2021Cell Biology