ImmunologybioRxiv
A Single Dose of Self-Transcribing and Replicating RNA Based SARS-CoV-2 Vaccine Produces Protective Adaptive Immunity In Mice
R. M. de Alwis, E. S. Gan, S. Chen…·E. E. Ooi
A single dose of the STARR-based SARS-CoV-2 vaccine LUNAR-COV19 induces protective adaptive immunity in mice, including strong antibody and CD8+ T cell responses, and full protection against viral challenge.
DOI 10.1016/j.ymthe.2021.04.001