Author

E. Allen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Microbiology· 3 Ecology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:ecology & biodiversity· 2 Assay:metagenomics· 2

Frequent Co-Authors

T. Lambe· 3 shared A. Spencer· 2 shared C. Bissett· 2 shared C. Gilbride· 2 shared H. Sharpe· 2 shared M. Ulaszewska· 2 shared S. Belij-Rammerstorfer· 2 shared S. C. Gilbert· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

T. Lambe

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

High affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells

R. W. Cochrane, R. A. Robino, B. Granger, E. Allen, S. Vaena, M. J. Romeo, A. A. de Cubas, S. Berto, L. M. R. Ferreira

This study shows that high-affinity CAR signaling in human Tregs leads to increased cytotoxicity and inflammatory cytokine production, while lower affinity reduces these effects.

bioRxiv · Mar 31, 2024Immunology

ChAdOx1 COVID vaccines express RBD open prefusion SARS-CoV-2 spikes on the cell surface

P. Zhang, S. Gilbert, J. Radecke, T. Ni, L. Mendonca, Y. Zhu, A. Howe, P. M. Shah, Y. Sheng, A.-S. Krebs, H. M. E. Duyvesteyn, E. Allen, T. Lambe, C. Bissett, S. Morris, , D. I. Stuart

This study determines the native structure of ChAdOx1-vectored SARS-CoV-2 vaccines on cell surfaces, showing prefusion spikes in one-RBD-up conformation and improved RBD exposure in HexaPro-stabilized variants.

bioRxiv · May 22, 2023Microbiology

Phenotypic and transcriptional response of Daphnia pulicaria to the combined effects of temperature and predation

A. Oliver, H. B. Cavalheri, T. G. Lima, N. T. Jones, S. Podell, D. Zarate, E. Allen, R. S. Burton, J. B. Shurin

This study examines how temperature and fish predation affect Daphnia pulicaria's physiology and gene expression, finding synergistic interactions between these stressors.

bioRxiv · Feb 24, 2022Ecology

Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop

Y. Hua, G. Vella, F. Rambow, E. Allen, A. A. Martinez, M. Duhamel, S. Junius, A. Smeets, D. Nittner, D. Laoui, S. Dimmeler, T. Hehlgans, A. Liston, G. Floris, D. Lambrechts, , G. Bergers

This paper shows that antiangiogenic immunotherapies convert postcapillary venules into high-endothelial venules that support TCF1+ T cell niches through a feed-forward loop involving CD8 and NK cells.

bioRxiv · Dec 24, 2021 · PreprintCancer Biology

Survival of hatchery grown native oysters is associated with specific gut-associated bacteria at various locations within the Puget Sound

E. Kunselman, J. J. Minich, M. Horwith, J. Gilbert, E. Allen

This study examines how gut-associated bacteria in Olympia oysters vary by location in Puget Sound and links these variations to oyster survival rates.

bioRxiv · Oct 19, 2021 · PreprintMicrobiology

A Single Dose of Self-Transcribing and Replicating RNA Based SARS-CoV-2 Vaccine Produces Protective Adaptive Immunity In Mice

R. M. de Alwis, E. S. Gan, S. Chen, Y. S. Leong, H. C. Tan, S. L. Zhang, C. Yau, D. Matsuda, E. Allen, P. Hartman, J. Park, M. Alayyoubi, H. Bhaskaran, A. Dukanovic, B. Bao, , E. E. Ooi

A single dose of the STARR-based SARS-CoV-2 vaccine LUNAR-COV19 induces protective adaptive immunity in mice, including strong antibody and CD8+ T cell responses, and full protection against viral challenge.

bioRxiv · Sep 3, 2020Immunology

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

S. P. Graham, R. K. McLean, A. J. Spencer, S. Belij-Rammerstorfer, D. Wright, M. Ulaszewska, J. C. Edwards, J. W. P. Hayes, V. Martini, N. Thakur, C. Conceicao, I. Dietrich, H. Shelton, R. Waters, A. Ludi, , T. Lambe

This study evaluates the immunogenicity of single and booster doses of the ChAdOx1 nCoV-19 vaccine in mice and pigs, finding that a booster significantly enhances antibody responses, especially in pigs.

bioRxiv · Jun 20, 2020Immunology

ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques

N. van Doremalen, T. Lambe, A. Spencer, S. Belij-Rammerstorfer, J. Purushotham, J. Port, V. Avanzato, T. Bushmaker, A. Flaxman, M. Ulaszewska, F. Feldmann, E. Allen, H. Sharpe, J. Schulz, M. Holbrook, , V. Munster

This study shows that the ChAdOx1 nCoV-19 vaccine reduces SARS-CoV-2 viral load and prevents pneumonia in rhesus macaques without causing immune-enhanced disease.

bioRxiv · May 13, 2020 · PreprintMicrobiology

Temporal, environmental, and biological drivers of the mucosal microbiome in a wild marine fish, Scomber japonicus

J. Minich, S. Petrus, J. D. Michael, T. P. Michael, R. Knight, E. Allen

This study examines how environmental and biological factors shape the mucosal microbiome of wild marine fish over time, identifying key drivers like temperature and fish age.

bioRxiv · Aug 1, 2019Ecology