The Lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope binding
M. Wallace, G. R. Fedorchak, R. Agrawal, R. M. Gilbert, J. Patel, S. Park, M. Paszek, J. Lammerding
This study shows that the Lamin A/C Ig-fold undergoes cell density-dependent conformational changes that affect antibody binding, without altering protein levels or nuclear mechanics.
bioRxiv · Nov 22, 2022Cell Biology