Author

G. R. Fedorchak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

J. Lammerding· 2 shared J. Patel· 2 shared A. J. Earle· 1 shared G. Bonne· 1 shared L. L. Wallrath· 1 shared M. Paszek· 1 shared M. Wallace· 1 shared P. Isermann· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

J. Lammerding

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2 papers

Recent·Most cited

The Lamin A/C Ig-fold undergoes cell density-dependent changes that alter epitope binding

M. Wallace, G. R. Fedorchak, R. Agrawal, R. M. Gilbert, J. Patel, S. Park, M. Paszek, J. Lammerding

This study shows that the Lamin A/C Ig-fold undergoes cell density-dependent conformational changes that affect antibody binding, without altering protein levels or nuclear mechanics.

bioRxiv · Nov 22, 2022Cell Biology

Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells

A. J. Earle, T. J. Kirby, G. R. Fedorchak, P. Isermann, J. Patel, S. Iruvanti, S. A. Moore, G. Bonne, L. L. Wallrath, J. Lammerding

This study shows that LMNA mutations cause nuclear envelope rupture and DNA damage in muscle cells, leading to disease through mechanical stress and DNA damage pathways.

bioRxiv · Aug 17, 2019Cell Biology