R. M. Lucero

Peripheral mutations underlie promiscuous transport of quaternary ammonium antiseptics by Small Multidrug Resistance transporters

The paper identifies peripheral mutations that enable promiscuous transport of quaternary ammonium antiseptics by SMR transporters, revealing that substrate preference changes through mutations outside the binding pocket.

Transport of metformin metabolites by guanidinium exporters of the Small Multidrug Resistance family

This study examines how bacterial SMR transporters handle metformin metabolites, showing they efficiently export guanylurea and providing insights into their function and potential role in microbial adaptation.