J. Hyun

Journey to the center of the phage; revealing the ejectosome of Pectobacterium bacteriophage {Phi}M1

This paper determines the cryo-EM structure of the ejectosome of bacteriophage {Phi}M1, revealing unique structural features and a novel DNA spooling mechanism.

Matrix-rigidity cooperates with biochemical cues in M2 macrophage activation through increased nuclear deformation and chromatin accessibility

This study shows matrix rigidity enhances M2 macrophage activation by altering nuclear mechanics and chromatin accessibility through cooperation with biochemical signals like IL4/13.

Peripheral mutations underlie promiscuous transport of quaternary ammonium antiseptics by Small Multidrug Resistance transporters

The paper identifies peripheral mutations that enable promiscuous transport of quaternary ammonium antiseptics by SMR transporters, revealing that substrate preference changes through mutations outside the binding pocket.

DNA micro-disk for the management of DNA-based data storage with index and write-once-read-many (WORM) memory features

This paper introduces DNA micro-disks with index and WORM memory features to improve DNA-based data storage reliability and accessibility.

RUNX3 regulates cell cycle-dependent chromatin dynamics by functioning as a pioneer factor of the restriction point

This study shows RUNX3 regulates chromatin dynamics at the restriction point by opening and closing target loci through recruitment of chromatin modifiers, influencing cell cycle progression and tumor development.

In vitro assembly of the Rous Sarcoma Virus capsid protein into hexamer tubes under physiological conditions.

This study shows RSV CA assembles into hexamer tubes in vitro under physiological conditions, with spacer peptide influencing layering and tube structure.