Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes
D. A. C. Heesterbeek, R. M. Muts, V. P. van Hensbergen, P. de Saint Aulaire, T. Wennekes, B. W. Bardoel, N. M. van Sorge, S. H. M. Rooijakkers
This study shows how MAC pores in Gram-negative bacteria's outer membrane make them more susceptible to immune system components like lysozyme and phospholipases, enhancing bacterial clearance.
bioRxiv · Jan 28, 2020Immunology