Host lung environment limits Aspergillus fumigatus germination through a SskA-dependent signaling response
M. E. Kirkland, M. Stannard, C. H. Kowalski, D. L. Mould, A. K. Caffrey-Carr, R. M. Temple, B. S. Ross, L. A. Lofgren, J. E. Stajich, R. A. Cramer, J. J. Obar
The paper identifies a SskA-dependent signaling pathway that limits Aspergillus fumigatus germination in the host lung environment, enhancing disease initiation and inflammation.
bioRxiv · Aug 27, 2021Microbiology