Author

R. Mazroui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

J.-P. Lambert· 2 shared P. Adjibade· 2 shared A. Caillier· 1 shared A. Zoubeidi· 1 shared B. Trudel· 1 shared E. I. J. Lelong· 1 shared F. Bordeleau· 1 shared F. Rondeau· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

J.-P. Lambert

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Author profile →

3 papers

Recent·Most cited

The RNA demethylases ALKBH5 and FTO regulate translation of the ATF4 mRNA in sorafenib-treated hepatocarcinoma cells

R. Mazroui, P. Adjibade

This study shows that ALKBH5 and FTO promote ATF4 mRNA translation in sorafenib-treated hepatocarcinoma cells, contributing to chemoresistance.

bioRxiv · Feb 9, 2024 · PreprintCancer Biology

Cell contractility-induced mechanical stress triggers eIF2α-regulated translation during early adhesion of mesenchymal-like cells

A. Caillier, M. Lavigne, J. Bergeman, N. Morin, F. Rondeau, J. Gouhier, B. Trudel, J.-P. Lambert, R. Mazroui, F. Bordeleau, M.-E. Huot

The paper identifies a mechanotransduction pathway where eIF2α phosphorylation during early adhesion regulates selective translation of proteins critical for adhesion and contractility in mesenchymal-like cells.

bioRxiv · Apr 19, 2022 · PreprintCell Biology

Prostate cancer resistance leads to a global deregulation of translation factors and unconventional translation of long non-coding RNAs

E. I. J. Lelong, P. Adjibade, F.-H. Joncas, G. Khelifi, V. Grenier St-Sauveur, A. Zoubeidi, J.-P. Lambert, P. Toren, R. Mazroui, S. M. I. Hussein

This study identifies global translational deregulation and unconventional translation of long non-coding RNAs in enzalutamide-resistant prostate cancer.

bioRxiv · Jan 5, 2021 · PreprintCancer Biology