Author

J.-P. Lambert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. Loehr· 2 shared R. Mazroui· 2 shared A. Caillier· 1 shared A. Lashgari· 1 shared A. Zoubeidi· 1 shared A.-C. Gingras· 1 shared B. Gonzalez-Badillo· 1 shared B. Trudel· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

J. Loehr

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Systematic profiling of the acetyl lysine machinery reveals a role for MAPKAPK2 in bromodomain inhibitor resistance

P.-E. Kougnassoukou Tchara, J. Loehr, L. Germain, Z. Steinhart, B. Gonzalez-Badillo, A. Lashgari, F. J. M. Chartier, M. Tucholska, S. Picaud, J. D. R. Knight, S. Angers, N. Bisson, C. R. Goding, E. Audet-Walsh, P. Filippakopoulos, , J.-P. Lambert

This study maps the acetyl lysine machinery interactions and identifies MAPKAPK2 as a factor contributing to resistance to BET bromodomain inhibitors in melanoma.

bioRxiv · Jul 22, 2024 · PreprintCancer Biology

Cell contractility-induced mechanical stress triggers eIF2α-regulated translation during early adhesion of mesenchymal-like cells

A. Caillier, M. Lavigne, J. Bergeman, N. Morin, F. Rondeau, J. Gouhier, B. Trudel, J.-P. Lambert, R. Mazroui, F. Bordeleau, M.-E. Huot

The paper identifies a mechanotransduction pathway where eIF2α phosphorylation during early adhesion regulates selective translation of proteins critical for adhesion and contractility in mesenchymal-like cells.

bioRxiv · Apr 19, 2022 · PreprintCell Biology

Prostate cancer resistance leads to a global deregulation of translation factors and unconventional translation of long non-coding RNAs

E. I. J. Lelong, P. Adjibade, F.-H. Joncas, G. Khelifi, V. Grenier St-Sauveur, A. Zoubeidi, J.-P. Lambert, P. Toren, R. Mazroui, S. M. I. Hussein

This study identifies global translational deregulation and unconventional translation of long non-coding RNAs in enzalutamide-resistant prostate cancer.

bioRxiv · Jan 5, 2021 · PreprintCancer Biology

JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage

J. Fages, C. Chailleux, J. Humbert, S.-M. Jang, J. Loehr, J.-P. Lambert, C. Jacques, D. Trouche, y. canitrot

This study identifies JMJD6 as essential for rDNA stability during DNA damage by facilitating nucleolar cap formation and NBS1 recruitment, independent of rDNA transcription inhibition.

bioRxiv · Nov 6, 2019Cell Biology