Author

R. P. Coppes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. H. Brouwers· 2 shared L. H. J. Sondorp· 2 shared L. Jansen· 2 shared S. Kruijff· 2 shared W. T. Zandee· 2 shared A. A. S. Gamez· 1 shared A. Jellema-de Bruin· 1 shared A. Kemper· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. H. Brouwers

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Author profile →

4 papers

Recent·Most cited

The Mayo Clinic Salivary Tissue-Organoid Biobanking: A Resource for Salivary Regeneration Research

S. M. M. Aalam, A. R. Varela, A. Khaderi, R. J. Mondesir, D.-G. Mun, A. Z. Ding, I. M. A. Lombaert, R. P. Coppes, C. P. Emperumal, A. Pandey, J. R. Janus, N. Kannan

The paper establishes a salivary regenerative biobank and identifies markers and proteomic signatures of salivary gland stem and progenitor cells.

bioRxiv · Feb 23, 2024 · PreprintCell Biology

Transposable Element Derepression-mediated IFN-I Signaling Enhances Stem/Progenitor Cell Activity After Irradiation

D. Cinat, R. van der Wal, M. Baanstra, A. A. S. Gamez, A. Jellema-de Bruin, U. Brouwer, M.-J. van Goethem, M. van Vugt, L. Barazzuol, R. P. Coppes

The paper shows that transposable element derepression triggers IFN-I signaling, boosting stem/progenitor cell activity after irradiation.

bioRxiv · Feb 14, 2024Cell Biology

Patient-Derived Medullary Thyroid Cancer Organoids; a Model for Patient-tailored Drug and PET-Tracer Screening

L. H. J. Sondorp, E. C. Jager, I. Farinha Antunes, R. Maturi, L. Jansen, W. T. Zandee, A. H. Brouwers, T. P. Links, R. P. Coppes, S. Kruijff

This paper establishes a patient-derived MTC organoid model for drug screening and PET tracer uptake analysis, showing successful culture and functional resemblance to native tissue.

bioRxiv · Sep 18, 2023 · PreprintCancer Biology

Patient-derived parathyroid organoids as tracer and drug-screening application model

M. E. Noltes, L. H. J. Sondorp, L. Kracht, I. F. Antunes, R. Wardenaar, W. Kelder, A. Kemper, W. Szymanski, W. T. Zandee, L. Jansen, A. H. Brouwers, R. P. Coppes, S. Kruijff

This study develops patient-derived parathyroid organoids that mimic parathyroid tissue function and respond to calcium and drugs, showing potential for therapeutic and imaging tracer research.

bioRxiv · Mar 24, 2022Cell Biology