Author

R. P. McCord

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 2 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:Hi-C· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:dimensionality reduction· 2

Frequent Co-Authors

P. Das· 3 shared R. Dos Reis Marques· 2 shared R. San Martin· 2 shared T. Shen· 2 shared Y. Xu· 2 shared A. G. von Arnim· 1 shared A. Gonzalez· 1 shared B. Pham· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

P. Das

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Author profile →

5 papers

Recent·Most cited

Node Features of Chromosome Structure Network and Their Connections to Genome Annotation

Y. Xu, P. Das, R. P. McCord, T. Shen

The paper investigates network properties of chromosome structure networks derived from Hi-C data and their connections to genome annotations, finding that semi-local properties better characterize biological features than local or diffusive features.

bioRxiv · Dec 29, 2023Biophysics

Amorphous calcium phosphate-coated surfaces as a model for bone microenvironment in prostate cancer

R. San Martin, P. Das, T. Xue, M. R. Brown, R. Dos Reis Marques, M. Essington, A. Gonzalez, R. P. McCord

The paper develops a cost-effective method to coat cell culture vessels with amorphous calcium phosphate to model the bone microenvironment and shows its effect on prostate cancer cell survival.

bioRxiv · Mar 20, 2023Cancer Biology

Enhancing Quantitative and Data Science Education for Graduate Students in Biomedical Science

L. J. Gross, R. P. McCord, S. M. LoRe, V. V. Ganusov, T. V. Hong, C. Strickland, D. Talmy, A. G. von Arnim, G. Wiggins

This paper develops a method to prioritize quantitative concepts for graduate biomedical science curricula based on faculty-identified key publications.

bioRxiv · Dec 3, 2021 · PreprintScientific Communication & Education

Alterations in chromosome spatial compartmentalization classify prostate cancer progression

R. San Martin, P. Das, R. Dos Reis Marques, Y. Xu, R. P. McCord

The paper uses Hi-C data to show that changes in chromatin compartmentalization classify prostate cancer progression, with specific gene clusters switching compartments and contributing to disease progression.

bioRxiv · Apr 15, 2021Cancer Biology

Characterizing the 3D structure and dynamics of chromosomes and proteins in a common contact matrix framework

R. J. Lindsay, B. Pham, T. Shen, R. P. McCord

This paper compares E-PCA and I-PCA methods on chromosome and protein contact matrices to reveal structural dynamics and differences across cell types and protein complexes.

bioRxiv · Feb 13, 2018Biophysics