R. J. Lindsay

Exaptation and de novo mutations transcend cryptic variations as drivers of adaptation in yeast

This study shows that yeast populations in predictable environments lose adaptive potential, with adaptation to stress driven by de novo mutations rather than pre-existing cryptic variations.

Molecular dynamics simulations illuminate the role of sequence context in the ELF3-PrD-based temperature sensing mechanism in plants

The paper uses molecular dynamics simulations to show how sequence context and polyQ tract length affect temperature-dependent condensate formation in ELF3-PrD, influencing plant growth responses.

Characterizing the 3D structure and dynamics of chromosomes and proteins in a common contact matrix framework

This paper compares E-PCA and I-PCA methods on chromosome and protein contact matrices to reveal structural dynamics and differences across cell types and protein complexes.