ImmunologybioRxivPreprint
In Vitro Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40
J. E. Wu, S. Manne, S. F. Ngiow…·E. J. Wherry
The paper establishes an in vitro model of CD8 T cell exhaustion and uses CRISPR screening to identify BHLHE40 as a regulator of T cell exhaustion differentiation.
DOI 10.1101/2023.04.17.537229