Author

E. T. Luning Prak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. M. Rosenfeld· 3 shared W. Meng· 3 shared A. E. Baxter· 2 shared A. B. Pernis· 1 shared A. J. Fike· 1 shared A. Pattekar· 1 shared A. R. Greenplate· 1 shared A. R. Weisman· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

A. M. Rosenfeld

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Author profile →

4 papers

Recent·Most cited

STAT3 signaling in B cells controls germinal center zone organization and recycling

A. J. Fike, S. B. Chodisetti, N. E. Wright, K. N. Bricker, P. D. Domeier, M. Maienschein-Cline, A. M. Rosenfeld, S. A. Luckenbill, J. L. Weber, N. M. Choi, E. T. Luning Prak, M. Mandal, M. R. Clark, Z. S. M. Rahman

This study shows STAT3 signaling in B cells controls germinal center zone organization and recycling, affecting long-lived plasma cell and memory B cell output.

bioRxiv · Aug 12, 2022Immunology

Sex-specific differences in the function and differentiation of ABCsmark TLR7-driven immunopathogenesis

E. Ricker, M. Manni, D. Flores-Castro, D. Jenkins, S. Gupta, J. Rivera-Correa, W. Meng, A. M. Rosenfeld, T. Pannellini, M. Bachu, Y. Chinenov, P. K. Sculco, R. Jessberger, E. T. Luning Prak, A. B. Pernis

The paper shows sex-specific differences in ABCs expansion, ISG signature upregulation, and differentiation in TLR7-driven immunopathogenesis, with Tlr7 duplication in males exacerbating disease severity.

bioRxiv · Jan 20, 2021 · PreprintImmunology

Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection

L. Kuri-Cervantes, M. B. Pampena, W. Meng, A. M. Rosenfeld, C. A. G. Ittner, A. R. Weisman, R. Agyekum, D. Mathew, A. E. Baxter, L. Vella, O. Kuthuru, S. Apostolidis, L. Bershaw, J. Dougherty, A. R. Greenplate, , M. R. Betts

The paper identifies broad immune perturbations in severe COVID-19, including innate and adaptive immune cell changes and heterogeneity in B cell responses and antibody production.

bioRxiv · May 18, 2020 · PreprintImmunology

Chronic viral infection promotes early germinal center exit of B cells and impaired antibody development.

R. P. Staupe, L. A. Vella, S. Manne, J. R. Giles, W. Meng, R. S. Herati, O. Khan, J. E. Wu, A. E. Baxter, E. T. Luning Prak, E. J. Wherry

This study shows chronic viral infection disrupts GC B cell fate decisions, leading to early exit and impaired antibody development.

bioRxiv · Nov 21, 2019 · PreprintImmunology