Structural insights into γH2Ax containing nucleosomes
R. Panigrahi, R. Edwards, M. T. Islam, J. Lu, A. Kulepa, T. H. Kim, J. N. M. Glover
The paper characterizes the interaction between MDC1 BRCT domains and γH2AX nucleosomes using cryo-EM, revealing structural insights into nucleosome stacking and its disruption by BRCT binding.
bioRxiv · Apr 30, 2023 · PreprintBiochemistry