Cancer BiologybioRxivPreprint
Hepatic JNK-mediated bile acid homeostasis regulates liver cancer through PPARα
E. Manieri, L. Esteban-Lafuente, E. Rodriguez…·G. Sabio
This study shows that hepatic JNK deficiency alters bile acid metabolism and promotes liver cancer via PPARα activation in mice on a high-fat diet.
DOI 10.1101/783761