BiophysicsbioRxiv
Mechanical Activation of MscL Revealed by a Locally Distributed Tension Molecular Dynamics Approach
R. R. Tatikonda, A. Anishkin, S. I. Sukharev, J. M. Vanegas
This paper introduces a new molecular dynamics method to simulate the mechanical activation of MscL, showing reproducible and reversible transitions to the open state with experimentally accurate parameters.
DOI 10.1016/j.bpj.2020.11.2274