Structure of the PfRCR complex which bridges the malaria parasite and erythrocyte during invasion
B. Farrell, N. Alam, M. Hart, A. Jamwal, R. Ragotte, H. Walters-Morgan, S. Draper, E. Knuepfer, M. K. Higgins
This paper determines the structure of the PfRCR complex using cryogenic-electron microscopy, revealing its modular architecture and interaction with erythrocyte receptors, which informs vaccine design.
bioRxiv · Jan 30, 2023Microbiology