Structural Insights into the Assembly and Regulation of 2'-O RNA Methylation by SARS-CoV-2 nsp16/nsp10
Anurag Misra, R. Rahisuddin, Manish Parihar, Shailee Arya, Thiruselvam Viswanathan, Nathaniel D. Jackson, Shan Qi, Siu‐Hong Chan, Reuben S. Harris, Luis Martínez‐Sobrido, Yogesh K. Gupta
This study presents a 2.4 Å crystal structure of the SARS-CoV-2 nsp16/nsp10 complex bound to Cap-1 RNA, revealing structural insights into its assembly and methylation mechanism.
Structure · Apr 11, 2025Peer-reviewedMicrobiology