Selective Vulnerability of Senescent Glioblastoma Cells to Bcl-XL Inhibition
M. Rahman, I. E. Olson, M. Mansour, L. P. Carlstrom, R. Sutiwisesak, R. Saber, K. Rajani, A. E. Warrington, A. Howard, M. Schroeder, S. Chen, P. A. Decker, Y. Zhu, I. F. Parney, S. Burma, , E. F. Sananikone
This study identifies Bcl-XL inhibition as a selective vulnerability of senescent glioblastoma cells following radiation or TMZ treatment.
bioRxiv · Jun 3, 2020Cancer Biology