Author

R. Scrutton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Qian· 2 shared H. Ausserwoger· 2 shared P. St George-Hyslop· 2 shared S. Qamar· 2 shared T. Sneideris· 2 shared C. Fischer· 1 shared C. M. Fischer· 1 shared N. Ermann· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiophysics

D. Qian

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2 papers

Recent·Most cited

Temperature-induced changes in protein interactions control RNA recruitment to G3BP1 condensates

C. M. Fischer, H. Ausserwoger, T. Sneideris, D. Qian, R. Scrutton, S. Qamar, P. St George-Hyslop, T. P. J. Knowles

The paper investigates how temperature affects G3BP1-RNA phase separation, revealing that while the phase boundary remains stable, stoichiometry and energetics shift, driven by entropic processes.

bioRxiv · Feb 2, 2024 · PreprintBiophysics

Linking modulation of bio-molecular phase behaviour with collective interactions

D. Qian, H. Ausserwoger, W. E. Arter, R. Scrutton, T. J. Welsh, T. Kartanas, N. Ermann, S. Qamar, C. Fischer, T. Sneideris, P. St George-Hyslop, R. V. Pappu, T. Knowles

This paper introduces a dominance analysis framework to determine the molecular mechanism of condensate modulation, demonstrating its application to G3BP1/RNA condensates disrupted by suramin.

bioRxiv · Nov 2, 2023 · PreprintBiophysics