S. Qamar

Temperature-induced changes in protein interactions control RNA recruitment to G3BP1 condensates

The paper investigates how temperature affects G3BP1-RNA phase separation, revealing that while the phase boundary remains stable, stoichiometry and energetics shift, driven by entropic processes.

Nanoscale profiling of evolving intermolecular interactions in ageing FUS condensates

This study characterizes the aging behavior of FUS condensates using microfluidic technology and surface-based techniques, revealing phase transitions and structural changes associated with material properties.

Linking modulation of bio-molecular phase behaviour with collective interactions

This paper introduces a dominance analysis framework to determine the molecular mechanism of condensate modulation, demonstrating its application to G3BP1/RNA condensates disrupted by suramin.

A hybrid CNN-Random Forest algorithm for bacterial spore segmentation and classification in TEM images

The paper introduces a hybrid CNN-Random Forest algorithm for segmenting and classifying bacterial spore layers in TEM images, achieving better robustness and generalization than other classifiers.

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes

This study shows ANXA11 biomolecular condensates couple protein and lipid phase states on lysosomal membranes through interactions with ALG2 and CALC.

Multiphase condensates from a kinetically arrested phase transition

This paper shows that multiphase biomolecular condensates form due to kinetic trapping during phase transitions, not thermodynamic stability, and explains how this leads to internal sub-compartments.

Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition

The paper shows that protein condensates undergo a liquid-to-solid transition under mechanical shear, revealing hydrogen bonding as a key factor.

High Resolution Biomolecular Condensate Phase Diagrams with a Combinatorial Microdroplet Platform

This paper introduces a microdroplet platform to rapidly generate high-resolution phase diagrams of biomolecular condensates and demonstrates its application in studying phase transitions.