Author

R. Sigrist

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

C. H. Gotfredsen· 1 shared J. M. A. Moreira· 1 shared L. D. O. Souza· 1 shared L. Ding· 1 shared M. Maleckis· 1 shared M. S. Cowled· 1 shared M. Wibowo· 1 shared P. Charusanti· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

C. H. Gotfredsen

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1 paper

Recent·Most cited

Maramycin, a cytotoxic isoquinolinequinone terpenoid produced through heterologous expression of a bifunctional indole prenyltransferase /tryptophan indole-lyase in S. albidoflavus

M. Maleckis, M. Wibowo, S. E. Williams, C. H. Gotfredsen, R. Sigrist, L. D. O. Souza, M. S. Cowled, P. Charusanti, T. Gren, S. Saha, J. M. A. Moreira, T. Weber, L. Ding

The paper reports the discovery of maramycin, a novel isoquinolinequinone alkaloid produced through heterologous expression of a bifunctional enzyme in Streptomyces albidoflavus, showing moderate cytotoxicity against prostate cancer cells.

bioRxiv · Feb 14, 2024Bioengineering