Author

M. Maleckis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

L. Ding· 2 shared M. Wibowo· 2 shared T. Gren· 2 shared T. Weber· 2 shared C. H. Gotfredsen· 1 shared C. M. Whitford· 1 shared E. B. Sterndorff· 1 shared J. M. A. Moreira· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

L. Ding

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Maramycin, a cytotoxic isoquinolinequinone terpenoid produced through heterologous expression of a bifunctional indole prenyltransferase /tryptophan indole-lyase in S. albidoflavus

M. Maleckis, M. Wibowo, S. E. Williams, C. H. Gotfredsen, R. Sigrist, L. D. O. Souza, M. S. Cowled, P. Charusanti, T. Gren, S. Saha, J. M. A. Moreira, T. Weber, L. Ding

The paper reports the discovery of maramycin, a novel isoquinolinequinone alkaloid produced through heterologous expression of a bifunctional enzyme in Streptomyces albidoflavus, showing moderate cytotoxicity against prostate cancer cells.

bioRxiv · Feb 14, 2024Bioengineering

Biosynthesis of the azoxy compound azodyrecin from Streptomyces mirabilis P8-A2

M. Maleckis, M. Wibowo, T. Gren, S. A. Jarmusch, E. B. Sterndorff, T. J. Booth, N. N. S. E. Henriksen, C. M. Whitford, X. Jiang, T. S. Jorgensen, L. Ding, T. Weber

This study identifies and characterizes the biosynthetic pathway for azodyrecin, an azoxy compound produced by Streptomyces mirabilis P8-A2, revealing key enzymes and gene cluster distribution across Streptomyces species.

bioRxiv · Oct 13, 2023Microbiology