R. Singer

Irreversible PDMS bonding using flame activation of adhesives for fabrication of microfluidic and organ-on-chip devices

This paper introduces a low-cost, flame-based method for irreversible PDMS bonding, enabling robust microfluidic and organ-on-chip fabrication with high bonding integrity.

mRNA Localization and Local Translation of the Microtubule Severing Enzyme, Fidgetin-Like 2, in Polarization, Migration and Outgrowth

This study shows that mRNA localization and local translation of FL2 in protrusions drive its expression at the leading edge after injury, with IMP1 and let-7 miRNA regulating this process.

Visualization of early RNA replication kinetics of SARS-CoV-2 by using single molecule RNA-FISH

This study uses smRNA-FISH to visualize SARS-CoV-2 gRNA and sgRNA replication kinetics, revealing asynchronous replication and RO formation within 2 hours post-infection.

Hidden species diversity in a living fossil vertebrate

The paper uses ddRAD sequencing and CT scans to identify a second species in the ancient Bowfin lineage, dating diversification to the Pleistocene.

MS2-TRIBE evaluates protein-RNA interactions and nuclear organization of transcription by RNA editing

The paper evaluates protein-RNA interactions and nuclear RNA organization using MS2-TRIBE, showing TRIBE can edit nearby nascent transcripts and form RNA regulatory domains.

Associations Between Nutrition, Gut Microbiome, and Health in A Novel Nonhuman Primate Model

The paper examines how diet and lifestyle affect the gut microbiome and health in red-shanked doucs, identifying microbial biomarkers of dysbiosis.