MicrobiologybioRxivPreprint
Contribution of 6mer seed toxicity to HIV-1 induced cytopathicity
A. Vaidyanathan, H. E. Taylor, T. J. Hope…·M. E. Peter
This paper identifies HIV-encoded miRNA HIV-miR-TAR-3p as a cytotoxic factor that induces cell death via DISE through a noncanonical 6mer seed, revealing a mechanism for HIV-induced cytopathicity.
DOI 10.1101/2022.10.01.510471