Cancer BiologybioRxiv
E-cadherin represses anchorage-independent growth in sarcomas through both signaling and mechanical mechanisms
M. K. Jolly, K. E. Ware, S. Xu…·J. A. Somarelli
This study identifies E-cadherin's role in suppressing sarcoma growth through both signaling (inhibiting p-CREB and TBX2) and mechanical (enhancing cell-cell adhesion) mechanisms.
DOI 10.1158/1541-7786.mcr-18-0763