Author

R. Veeranan-Karmegam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:Drosophila· 4 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

G. B. Gonsalvez· 5 shared H. Neiswender· 4 shared C. H. Goldman· 2 shared F. C. Baker· 2 shared B. Mysona· 1 shared F. Baker· 1 shared J. Zhao· 1 shared K. Bollinger· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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5 shared papersCell Biology

G. B. Gonsalvez

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5 papers

Recent·Most cited

The Bicaudal-D/Egalitarian complex defines the specificity of cargo transport by Dynein.

F. C. Baker, W. Lu, M. Lakonishok, H. Neiswender, R. Veeranan-Karmegam, P. Allen, S. Badieyan, M. A. Cianfrocco, V. Gelfand, G. B. Gonsalvez

This study identifies BicD cargo interactome and shows that Egl is required for BicD to link cargos to Dynein, with a SMA mutation affecting cargo transport and mobility.

bioRxiv · Sep 11, 2023 · PreprintCell Biology

Defining the Ligand-dependent Interactome of the Sigma 1 Receptor

J. Zhao, R. Veeranan-Karmegam, F. Baker, B. Mysona, P. Bagchi, Y. Liu, S. Smith, G. B. Gonsalvez, K. Bollinger

This study defines the ligand-dependent interactome of the Sigma 1 Receptor using biotinylation and mass spectrometry, revealing novel interactions and functional roles in cholesterol metabolism.

bioRxiv · Jun 22, 2022 · PreprintCell Biology

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor.

F. C. Baker, H. Neiswender, R. Veeranan-Karmegam, G. B. Gonsalvez

The paper identifies Egalitarian's interactome using proximity biotin ligation in Drosophila egg chambers, revealing novel partners and a nanobody-based strategy for interactome mapping.

bioRxiv · Jul 1, 2021Cell Biology

Dynein light chain-dependent dimerization of Egalitarian is essential for maintaining oocyte fate in Drosophila.

H. Neiswender, C. H. Goldman, R. Veeranan-Karmegam, G. B. Gonsalvez

This study shows that Dlc-mediated dimerization of Egl is essential for mRNA binding and oocyte fate in Drosophila, but artificial dimerization only partially rescues these functions.

bioRxiv · May 12, 2021Cell Biology

Egalitarian binding partners, Dynein Light Chain and Bicaudal-D, act sequentially to link mRNA to the Dynein motor

C. H. Goldman, R. Veeranan-Karmegam, H. Neiswender, G. B. Gonsalvez

The paper identifies the role of Dlc in promoting Egl dimerization, which is essential for RNA binding and subsequent association with the Dynein motor for mRNA localization.

bioRxiv · Feb 14, 2019Cell Biology