Author

R. Vuillefroy de Silly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Seijo· 1 shared G. Coukos· 1 shared I. Crespo· 1 shared L. Pericou· 1 shared M. Irving· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

B. Seijo

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1 paper

Recent·Most cited

Cell BiologybioRxivDec 15, 2023

Acidity-induced dysfunction of CD8+ T cells is characterized by impaired IL-2 responsiveness and perturbations to mTORC1 signaling and c-Myc levels

R. Vuillefroy de Silly, L. Pericou, B. Seijo…·M. Irving

This study shows that low pH impairs CD8+ T cell function by reducing IL-2 responsiveness, disrupting mTORC1 signaling, and altering c-Myc levels and amino acid metabolism.

DOI 10.1038/s44318-024-00235-w

humanproteomics

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