Author

R. W. Farndale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bonna· 1 shared B. Zuo· 1 shared D. Bihan· 1 shared D. Chen· 1 shared J. Llewellyn· 1 shared P. A. Janmey· 1 shared R. G. Wells· 1 shared S. W. Manka· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. Bonna

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2 papers

Recent·Most cited

Versican binds collagen via its G3 domain and regulates the organization and mechanics of collagenous matrices

D. Chen, Y. Du, J. Llewellyn, A. Bonna, B. Zuo, P. A. Janmey, R. W. Farndale, R. G. Wells

This study identifies versican as a collagen-binding protein that regulates collagen matrix organization and mechanics through its G3 domain.

bioRxiv · Mar 27, 2022Cell Biology

Structural studies of MMP-3 interaction with triple-helical collagen introduce the enzyme’s new roles in tissue remodelling

S. W. Manka, D. Bihan, R. W. Farndale

This study identifies MMP-3 interaction sites on collagen II and III using triple-helical peptides, revealing cooperative binding between its catalytic and hemopexin domains.

bioRxiv · Sep 3, 2019 · PreprintBiochemistry