Simultaneous proteome localization and turnover analysis reveals spatiotemporal dynamics of unfolded protein responses
J. Currie, V. Manda, S. K. Robinson, C. Lai, V. Agnihotri, V. Hidalgo, R. W. Ludwig, K. Zhang, Z. V. Wang, J.-W. Rhee, M. P. Y. Lam, E. Lau
This study introduces SPLAT, a proteomics method to analyze protein turnover and localization simultaneously, revealing spatiotemporal changes in the unfolded protein response in human cells.
bioRxiv · Jan 4, 2023Cell Biology