Author

C. Franco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biophysics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Organism:chicken / avian· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Chaperon· 1 shared A. Deas-Just· 1 shared A. Figueiredo· 1 shared A. G. Murzin· 1 shared A. Pena· 1 shared B. Cauli· 1 shared B. Ghetti· 1 shared B. Le Gac· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPhysiology

A. Chaperon

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W

C. Qi, S. Lovestam, A. G. Murzin, S. Peak-Chew, C. Franco, M. Bogdani, C. Latimer, J. R. Murrell, P. W. Cullinane, Z. Jaunmuktane, T. D. Bird, B. Ghetti, S. H. W. Scheres, M. Goedert

The paper determines the structures of tau filaments in individuals with MAPT mutations V337M and R406W using cryo-EM, finding the Alzheimer fold in all cases and a new triple filament assembly.

bioRxiv · Apr 29, 2024 · PreprintBiophysics

Astrocyte aquaporin mediates a tonic water efflux maintaining brain homeostasis

C. Pham, Y. Komaki, A. Deas-Just, B. Le Gac, C. Mouffle, C. Franco, A. Chaperon, V. Vialou, T. Tsurugizawa, B. Cauli, D. Li

This study shows astrocyte aquaporin 4 mediates a tonic water efflux that maintains brain water homeostasis, astrocyte volume, and extracellular space remodeling.

bioRxiv · Oct 3, 2023Physiology

A non-genetic model of vascular shunts informs on the cellular mechanisms of formation and resolution of arteriovenous malformations

M. Ouarne, A. Pena, D. Ramalho, N. Conchinha, T. Costa, A. Figueiredo, M. Saraiva, Y. Carvalho, L. Misikova, P. Oh, C. Franco

This study identifies EC volume changes as the key mechanism for AV shunt formation and regression, using a non-genetic model in mice.

bioRxiv · Aug 21, 2023Cell Biology

Harmonizing labeling and analytical strategies to obtain protein turnover rates in intact adult animals.

D. E. Hammond, D. M. Simpson, C. Franco, M. W. Muelas, J. Waters, R. W. Ludwig, M. C. Prescott, J. L. Hurst, R. J. Beynon, E. Lau

This study compares protein turnover rates in mouse tissues using two labeling methods, showing they yield similar results for long-lived proteins but require adjustments for short-lived proteins.

bioRxiv · Dec 13, 2021Physiology

New insights of the local immune response against both fertile and infertile hydatid cysts

C. Hidalgo, C. Stoore, K. Strull, C. Franco, F. Correa, M. Jimenez, M. Hernandez, K. Lorenzatto, H. B. Ferreira, N. Galanti, R. Paredes

The paper investigates immune infiltration in fertile and infertile hydatid cysts, finding that immune cells disrupt the laminated layer in infertile cysts, potentially causing infertility.

bioRxiv · Aug 13, 2018Immunology