Inhibition of Metastatic Uveal Melanoma Cell Proliferation by the Histone Deacetylase 6 Inhibitor, Ricolinostat, is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression
H. Sundaramurthi, S. Garcia-Mulero, K. Slater, S. Marcone, J. M. Piulats, R. W. Watson, D. Tobin, L. Jensen, B. N. Kennedy
This study shows that ACY-1215 inhibits metastatic uveal melanoma cell growth in vitro and in vivo by reducing p-ERK and MITF signaling.
bioRxiv · Oct 28, 2021 · PreprintCancer Biology