Author

L. Jensen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Pharmacology & Toxicology· 2 Biochemistry· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Organism:zebrafish· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

S. E. Degn· 2 shared A. B. Rovsing· 1 shared A. Benetti· 1 shared A. C. Girardi· 1 shared A. D. Papanastasiou· 1 shared A. J. Howarth· 1 shared A. L. Yokom· 1 shared A. Malita· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersImmunology

S. E. Degn

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A minimal two-residue C-terminal truncation of AID in adult-onset hyper-IgM syndrome type 2 (HIGM2)

K. Green, A. B. Rovsing, E. Terczynska-Dyla, L. Jensen, K. Machalica, J. H. Wolff, L. Westerberg, C. S. Larsen, L. Lin, J. G. Mikkelsen, J. M. B. Jensen, S. E. Degn

This study identifies a two-residue C-terminal truncation variant in AID causing adult-onset HIGM2 and shows it disrupts CSR and SHM.

bioRxiv · Nov 2, 2026 · PreprintImmunology

Extrafollicular responses are sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus

L. F. Voss, A. J. Howarth, T. R. Wittenborn, S. Hummelgaard, K. Juul-Madsen, K. S. Kastberg, M. K. Pedersen, L. Jensen, A. D. Papanastasiou, T. Vorup-Jensen, K. Weyer, S. E. Degn

This study shows that blocking germinal centers does not prevent lupus progression and instead accelerates extrafollicular autoimmunity.

bioRxiv · Mar 4, 2022Immunology

Inhibition of Metastatic Uveal Melanoma Cell Proliferation by the Histone Deacetylase 6 Inhibitor, Ricolinostat, is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression

H. Sundaramurthi, S. Garcia-Mulero, K. Slater, S. Marcone, J. M. Piulats, R. W. Watson, D. Tobin, L. Jensen, B. N. Kennedy

This study shows that ACY-1215 inhibits metastatic uveal melanoma cell growth in vitro and in vivo by reducing p-ERK and MITF signaling.

bioRxiv · Oct 28, 2021 · PreprintCancer Biology

Reconstitution of cargo-induced LC3 lipidation in mammalian selective autophagy

C. Chang, X. Shi, L. Jensen, A. L. Yokom, D. Fracchiolla, S. Martens, J. H. Hurley

This study investigates how different cargo receptors stimulate LC3 lipidation in selective autophagy using GUVs and shows varying requirements for autophagy core complexes.

bioRxiv · Jan 8, 2021Biochemistry

The gut hormone Allatostatin C regulates food intake and metabolic homeostasis under nutrient stress

O. Kubrak, L. Jensen, N. Ahrentloev, T. Koyama, A. Malita, M. T. Naseem, M. Lassen, S. Nagy, M. J. Texada, K. Halberg, K. Rewitz

bioRxiv · Dec 5, 2020 · PreprintPhysiology

Empagliflozin inhibits proximal tubule NHE3 activity, preserves GFR and restores euvolemia in non-diabetic heart failure rats

F. A. Borges-Junior, D. Silva dos Santos, A. Benetti, R. O. Crajoinas, E. Antonio, L. Jensen, B. Caramelli, G. Malnic, P. Tucci, A. C. Girardi

bioRxiv · Jul 16, 2020Pharmacology & Toxicology

Calcitriol and Non-Calcemic Vitamin D Analogue, 22 Oxacalcitriol, Attenuate Developmental and Pathological Ocular Angiogenesis Ex Vivo and In Vivo

S. Merrigan, B. Park, Z. Ali, L. Jensen, T. Corson, B. Kennedy

This study validates the anti-angiogenic effects of calcitriol and 22-oxacalcitriol in ocular models, showing reduced choroidal angiogenesis and improved safety profiles.

bioRxiv · Jan 9, 2019Pharmacology & Toxicology