R. Wigneshweraraj

Global RNA interactome of nitrogen starved Escherichia coli uncovers a conserved post-transcriptional regulatory axis required for optimal growth recovery

This study maps the Hfq-mediated RNA interactome in nitrogen-starved E. coli, revealing SdsR's role in post-transcriptional regulation during long-term growth arrest and recovery.

Enhancing the antibacterial function of probiotic Escherichia coli Nissle: when less is more

This study shows that reducing the production of a heterologous bacteriocin in a probiotic Escherichia coli strain enhances its antibacterial efficacy while minimizing fitness costs.

The RNA polymerase gene specificity factor sigma 54 is required for homogeneous non-planktonic growth of uropathogenic Escherichia coli

This study identifies sigma 54 as essential for homogeneous non-planktonic growth in uropathogenic E. coli, revealing a non-canonical function beyond its canonical role in transcription initiation.

The adaptive response to long term nitrogen starvation in Escherichia coli requires the breakdown of allantoin

This study investigates how Escherichia coli adapts to long-term nitrogen starvation by revealing the necessity of allantoin degradation for optimal growth recovery.

The assembly of Hfq into foci-like structures in response to long-term nitrogen starvation in Escherichia coli

This study shows Hfq forms reversible foci in E. coli during long-term nitrogen starvation, independent of gene expression and NtrC, aiding adaptation to nutrient stress.

Xenogeneic regulation of the ClpCP protease of Bacillus subtilis by a phage-encoded adaptor-like protein

This study identifies Gp53, a phage-encoded protein that modulates the ClpCP protease of Bacillus subtilis to alter the host proteome, aiding phage progeny production.

A T7 phage factor required for managing RpoS in Escherichia coli

This paper identifies Gp5.7 as a T7 phage protein that inhibits EσS in stationary phase E. coli, enabling T7 development in both exponential and stationary growth phases.