ImmunologybioRxivPreprint
The glucocorticoid dexamethasone impairs the expression of anti-viral mediators in activated macrophages by inhibiting both expression and function of interferon beta.
J. D. O'Neil, O. O. Bolimowska, S. A. Clayton…·A. R. Clark
This study shows dexamethasone inhibits antiviral gene expression in macrophages by suppressing IFNβ expression and downstream interferon-regulated genes.