Temporal Metabolic Characteristics and Transcriptomic Landscape of Islets and Liver Reveal Dynamic Pathophysiology and Interorgan Crosstalk in High-fat Diet-induced Diabetes
R. Gao, Q. Fu, H.-M. Jiang, M. Shen, R.-L. Zhao, Y. Qian, Y.-Q. He, K.-F. Xu, X.-Y. Xu, H. Chen, Q. Zhang, T. Yang
This study examines the temporal metabolic and transcriptomic changes in islets and liver of mice on high-fat diet, revealing dynamic pathophysiology and interorgan crosstalk in diabetes.
bioRxiv · Aug 21, 2020Cell Biology