Author

R.-P. Charles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Arcaro· 1 shared A. Stooss· 1 shared D. Ruffieux-Daidie· 1 shared J. Klukowska-Rötzler· 1 shared M. A. Roelli· 1 shared M. Kind· 1 shared M. S. Dettmer· 1 shared O. ElMokh· 1 shared

Activity by Year

2017-2017 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Arcaro

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2 papers

Recent·Most cited

PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors.

M. A. Roelli, D. Ruffieux-Daidie, A. Stooss, O. ElMokh, W. A. Phillips, M. S. Dettmer, R.-P. Charles

This study shows that PIK3CAH1047R mutations cause resistance to BRAFV600E inhibitors in thyroid tumors by paradoxically activating the ERK pathway.

bioRxiv · Jul 18, 2017Cancer Biology

Questioning the role of selected somatic PIK3C2B mutations in squamous non-small cell lung cancer oncogenesis.

M. Kind, J. Klukowska-Rötzler, S. Berezowska, A. Arcaro, R.-P. Charles

This study screens for PIK3C2B mutations in NSCLC-SQCC and finds no oncogenic effects, suggesting a minor role in SQCC oncogenesis.

bioRxiv · Jul 17, 2017Cancer Biology